Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103349 | 0.88 | GSK3B (0.61) | TSHRTDP1L3MBTL1CYP3A4CES1 | |
| SCHEMBL8103346 | 0.84 | NPC1 (0.43) | TSHRL3MBTL1ALDH1A1CYP3A4LMNA | |
| SCHEMBL3702935 | 0.81 | TSHR (0.50) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5681872 | 0.80 | ALDH1A1 (0.64) | ALDH1A1CES2CES1LMNACYP1A2 | |
| SCHEMBL10752669 | 0.80 | PARP10 (0.52) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL27520267 | 0.80 | CA1 (0.53) | TSHRTDP1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11442931 | 0.80 | PGR (0.44) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL9840012 | 0.80 | ALDH1A1 (0.61) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL3703925 | 0.80 | TDP1 (0.56) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5026930 | 0.79 | PGR (0.47) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036642-A | Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof | 江西农业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-116769741-B | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-115557865-B | Thioether-promoted cysteine-based bioconjugate method | 南京工业大学 | 2024-05-14 | — | — | CN | claimed |
| CN-116769741-A | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-115557865-A | Thioether-promoted cysteine-based bioconjugation method | 南京工业大学 | 2023-01-03 | — | — | CN | claimed |
| CN-113880786-A | Synthesis method and antioxidant application of camphene aldehyde thiazole hydrazone derivative | 江西农业大学 | 2022-01-04 | — | — | CN | claimed |
| CN-110305048-A | One kind preparing α-sulfuryl ketone compounds synthetic method by α, α-two bromo ketone one kettle way | 温州大学 | 2019-10-08 | — | — | CN | claimed |
| CN-105061356-A | Synthetic method of 2-amino-5-arylthiazole | SHANGHAI RAINBOW CHEMISTRY CO LTD | 2015-11-18 | — | — | CN | claimed |
| EP-0143711-B1 | DERIVATIVES OF N-(METHOXYPHENACYL)AMINE, THEIR THERAPEUTICAL USE AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-08-12 | — | — | EP | claimed |
| CN-122036642-A | Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof | 江西农业大学 | 2026-05-15 | — | — | CN | disclosed |
| EP-3810143-B1 | NADPH OXIDASE INHIBITORS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND APPLICATION THEREOF | TAIWANJ PHARMACEUTICALS CO LTD (TW) | 2025-04-16 | — | — | EP | disclosed |
| CN-118480006-A | Novel pyridazinone compound and preparation method and application thereof | 郑州大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-116769741-B | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-116947743-A | Nitrosothiol compound and synthesis method and application thereof | 南京雷正医药科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-0016277-A1 | 2-Carbonyl-3-hydroxy-alkenonitriles, their use as anti-arthritic agents and processes for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-10-01 | — | — | EP | disclosed |
| US-4181677-A | ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-01-01 | — | — | US | disclosed |
| US-4173650-A | ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-11-06 | — | — | US | disclosed |
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |