Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906842 | 0.84 | TSHR (0.42) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL7364076 | 0.83 | GABRP (0.38) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL19815863 | 0.78 | TSHR (0.43) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL29115925 | 0.78 | TSHR (0.43) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL30661793 | 0.78 | TSHR (0.43) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Hydrochloric Acid SCHEMBL17747395 | 0.76 | TSHR (0.42) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Bicarbonate SCHEMBL16668716 | 0.72 | FDPS (0.49) | TSHRLMNAARG1CYP1A2CYP2D6 | |
| SCHEMBL9506256 | 0.69 | PLG (0.57) | PLGPLATLMNAARG1GABRR1 | |
| SCHEMBL3656998 | 0.69 | — | — | |
| SCHEMBL15594537 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742903-A4 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0742903-A1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| WO-1995020763-A1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1995-08-03 | — | — | WO | disclosed |