Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 8/20 | 0.46 |
| ▸ | CHUK | O15111 | 7/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | CDK11B | P21127 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4980052 | 0.83 | IKBKB (0.67) | IKBKBCHUKCDK9ERN1RPS6KA4 | |
| SCHEMBL8118931 | 0.81 | CUL4A (0.52) | IKBKBCHUKCDK9ERN1RPS6KA4 | |
| SCHEMBL4981355 | 0.81 | IKBKB (0.66) | IKBKBCHUKCDK9ERN1RPS6KA4 | |
| SCHEMBL21642521 | 0.79 | BRD4 (0.48) | PTPN1CDK9CCNT1BRD4 | |
| SCHEMBL8117461 | 0.77 | TYMS (0.57) | IKBKBCHUKKDM4ELMNAALDH1A1 | |
| SCHEMBL8116946 | 0.75 | ALDH1A1 (0.47) | IKBKBCHUKCDK9CCNT1ALDH1A1 | |
| SCHEMBL121514 | 0.72 | IKBKB (0.46) | IKBKBCHUKKDM4ELMNAALDH1A1 | |
| SCHEMBL10845609 | 0.72 | GRIN2D (0.42) | — | |
| SCHEMBL8117112 | 0.68 | GRIA1 (0.56) | KDM4ELMNAALDH1A1MAPTHTT | |
| SCHEMBL8118650 | 0.67 | GRIN2D (0.49) | IKBKBPTPN1CDK9KDM4ECCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865442-B1 | IMIDAZO[1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOSCAMA BIOMED CHIM FARMA (IT) | 2000-07-05 | — | — | EP | disclosed |