Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119071 | 0.83 | HTR3E (0.39) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL124220 | 0.83 | IKBKB (0.43) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8102963 | 0.80 | CUL4A (0.51) | KDM4EALDH1A1HPGDNPC1GLA | |
| SCHEMBL3496046 | 0.78 | HTR3E (0.40) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL121472 | 0.78 | HTR3E (0.45) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL24832295 | 0.78 | IKBKB (0.45) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL30973203 | 0.78 | IKBKB (0.45) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL13077027 | 0.78 | IKBKB (0.66) | KDM4EALDH1A1MAPTMEN1POLB | |
| SCHEMBL120846 | 0.76 | MAPK8 (0.54) | KDM4EALDH1A1HPGDMEN1GLA | |
| SCHEMBL30578099 | 0.76 | MAPK8 (0.54) | KDM4EALDH1A1HPGDMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124287-A | TREATING DEPRESSION | BIOMEDICA FOSCAMA INDUSTRIA CHIMICOFARMACEUTICA S.P.A. (IT) | 2000-09-26 | — | — | US | disclosed |
| EP-0865442-B1 | IMIDAZO[1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOSCAMA BIOMED CHIM FARMA (IT) | 2000-07-05 | — | — | EP | disclosed |