Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2542920 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRMAPT | |
| SCHEMBL274867 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL2014792 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL14798059 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL17744969 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL1654500 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL258956 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL648618 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL1603841 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 | |
| SCHEMBL15526298 | 0.69 | LMNA (0.63) | ALDH1A1POLBCYP2C9LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |