Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104386 | 1.00 | L3MBTL1 (0.53) | L3MBTL1TSHRNPSR1KMT2AALDH1A1 | |
| SCHEMBL8101513 | 0.93 | L3MBTL1 (0.46) | L3MBTL1TSHRNPSR1ALDH1A1GAA | |
| SCHEMBL8097865 | 0.90 | L3MBTL1 (0.46) | L3MBTL1TSHRNPSR1KMT2AALDH1A1 | |
| SCHEMBL7513044 | 0.90 | ATM (0.48) | L3MBTL1TSHRNPSR1KMT2AALDH1A1 | |
| SCHEMBL8088954 | 0.88 | ATM (0.46) | L3MBTL1TSHRNPSR1KMT2AALDH1A1 | |
| SCHEMBL8105135 | 0.85 | L3MBTL1 (0.45) | L3MBTL1TSHRNPSR1GAASMN1; SMN2 | |
| SCHEMBL8103798 | 0.82 | L3MBTL1 (0.39) | L3MBTL1TSHRNPSR1KMT2AALDH1A1 | |
| SCHEMBL8095905 | 0.82 | GSK3B (0.38) | L3MBTL1TSHRNPSR1ATM | |
| SCHEMBL8097933 | 0.82 | GPBAR1 (0.42) | GAA | |
| SCHEMBL8098510 | 0.81 | SMN1; SMN2 (0.42) | L3MBTL1TSHRKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862435-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | claimed |
| EP-0862435-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-09-09 | — | — | EP | claimed |
| WO-1997018813-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-05-29 | — | — | WO | claimed |
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0862435-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0862435-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997018813-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-05-29 | — | — | WO | disclosed |