Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101513 | 0.91 | L3MBTL1 (0.46) | L3MBTL1TSHRNPSR1ATMGAA | |
| SCHEMBL8103584 | 0.90 | L3MBTL1 (0.53) | L3MBTL1TSHRNPSR1ATMGAA | |
| SCHEMBL8104386 | 0.90 | L3MBTL1 (0.53) | L3MBTL1TSHRNPSR1ATMGAA | |
| SCHEMBL7513044 | 0.89 | ATM (0.48) | L3MBTL1TSHRNPSR1ATMGAA | |
| SCHEMBL8105135 | 0.87 | L3MBTL1 (0.45) | L3MBTL1TSHRNPSR1ATMGAA | |
| SCHEMBL8088954 | 0.87 | ATM (0.46) | L3MBTL1TSHRNPSR1ATMGAA | |
| SCHEMBL8095905 | 0.85 | GSK3B (0.38) | L3MBTL1TSHRNPSR1ATMALOX12 | |
| SCHEMBL8097933 | 0.85 | GPBAR1 (0.42) | GAAMAPT | |
| SCHEMBL8095399 | 0.84 | CYP3A4 (0.44) | L3MBTL1SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL8088811 | 0.84 | GPR119 (0.44) | L3MBTL1TSHRNPSR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |