Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800827 | 0.81 | KCNH2 (0.37) | HSD17B10NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8100162 | 0.74 | HDAC1 (0.31) | TDP1 | |
| SCHEMBL7808523 | 0.69 | TDP1 (0.33) | KCNH2TDP1 | |
| SCHEMBL8099970 | 0.68 | KDM4E (0.32) | HSD17B10NPC1KDM4EALDH1A1MAPT | |
| SCHEMBL8075185 | 0.66 | — | — | |
| SCHEMBL3545 | 0.59 | L3MBTL1 (0.57) | HSD17B10NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16291133 | 0.59 | L3MBTL1 (0.57) | HSD17B10NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7227898 | 0.57 | L3MBTL1 (0.50) | HSD17B10NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7812052 | 0.57 | HSD17B10 (0.34) | HSD17B10NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20837438 | 0.57 | HSD17B10 (0.48) | HSD17B10NPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |