Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749042 | 0.83 | CCR5 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6749186 | 0.81 | CCR5 (0.33) | — | |
| SCHEMBL6747648 | 0.79 | BRD4 (0.32) | — | |
| SCHEMBL8400472 | 0.73 | ESR2 (0.31) | ESR2 | |
| SCHEMBL7330314 | 0.70 | — | — | |
| SCHEMBL9808457 | 0.69 | CYP1A2 (0.33) | — | |
| SCHEMBL10773607 | 0.69 | CA1 (0.35) | ESR2 | |
| SCHEMBL79061 | 0.69 | — | — | |
| Ethylene Glycol SCHEMBL9597725 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL9559079 | 0.69 | ESR2 (0.50) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661271-B1 | AZEPINE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS SIGMA-RECEPTOR LIGANDS | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0661271-A1 | AZEPINE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-07-05 | — | — | EP | disclosed |