SCHEMBL8103753

SCHEMBL8103753

CCc1ccc(NC(=S)SC)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.54
NPC1 O15118 4/20 0.54
SMN1; SMN2 Q16637 4/20 0.53
POLB P06746 1/20 0.51
MAPT P10636 5/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 1/20 0.50
KMT2A Q03164 1/20 0.50
SRC P12931 1/20 0.49
HPGD P15428 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
TP53 P04637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19101057 0.85 KDM4E (0.62) MAPTALDH1A1KDM4EKMT2AL3MBTL1
SCHEMBL27614505 0.85 RAB9A (0.51) RAB9ANPC1SMN1; SMN2POLBMAPT
SCHEMBL27804922 0.82 KDM4E (0.49) MAPTKDM4EKMT2A
SCHEMBL9453953 0.81 RAB9A (0.66) RAB9ANPC1SMN1; SMN2POLBMAPT
SCHEMBL18735412 0.79 RAB9A (0.59) RAB9ANPC1SMN1; SMN2POLBMAPT
SCHEMBL10092552 0.79 RAB9A (0.58) RAB9ANPC1SMN1; SMN2POLBMAPT
SCHEMBL2300811 0.78 GRIN2D (0.58) RAB9ANPC1SMN1; SMN2POLBMAPT
SCHEMBL17469336 0.76 ALDH1A1 (0.64) RAB9ANPC1SMN1; SMN2POLBMAPT
SCHEMBL26033861 0.76 RAB9A (0.54) RAB9ANPC1SMN1; SMN2POLBMAPT
SCHEMBL5881946 0.76 MAPT (0.71) RAB9ANPC1SMN1; SMN2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6121476-A Process for preparing dithiocarbonimide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-19 US disclosed
US-5962723-A Method for producing benzyl bromide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-10-05 US disclosed
CN-1218033-A Method of producing benzyl bromide derivatives SUMITOMO CHEMICAL CO (JP) 1999-06-02 CN disclosed
EP-0908446-A1 Method for producing benzyl bromide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-14 EP disclosed
EP-0811612-B1 Process for preparing dithiocarbonimide derivatives SUMITOMO CHEMICAL CO (JP) 1999-03-03 EP disclosed
CN-1169989-A Process for preparing dithiocarbonimide derivatives SUMITOMO CHEMICAL CO (JP) 1998-01-14 CN disclosed
EP-0811612-A1 Process for preparing dithiocarbonimide derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-12-10 EP disclosed