Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.41 |
| ▸ | FNTA | P49354 | 11/20 | 0.40 |
| ▸ | FNTB | P49356 | 11/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088439 | 0.87 | FNTA (0.52) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8098288 | 0.86 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8095903 | 0.86 | CYP11B1 (0.45) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097850 | 0.84 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2MEN1 | |
| SCHEMBL8088935 | 0.84 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2MEN1 | |
| SCHEMBL8095888 | 0.84 | FNTA (0.42) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8088208 | 0.84 | FNTA (0.44) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8103799 | 0.84 | CYP11B1 (0.48) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8426462 | 0.84 | CYP11B1 (0.48) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL446560 | 0.83 | FNTA (0.45) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |