Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781985 | 1.00 | LMNA (0.46) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11102654 | 0.92 | LMNA (0.48) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8123526 | 0.89 | CA2 (0.49) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1042355 | 0.89 | LMNA (0.46) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL438614 | 0.89 | CA2 (0.49) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6973472 | 0.89 | CA2 (0.57) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6973466 | 0.89 | CA2 (0.57) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10832816 | 0.89 | CA2 (0.51) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1019038 | 0.85 | FFAR1 (0.49) | LMNACA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1018787 | 0.85 | FFAR1 (0.49) | LMNACA2SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136825-A | ANTIDEPRESSANTS AND CENTRAL NERVOUS SYSTEM AGENTS | KNOLL AKTIENGESELLSCHAFT | 2000-10-24 | — | — | US | disclosed |