Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104175 | 1.00 | PTGIR (0.66) | PTGIRKDM4ETSHRHSD17B10EGLN3 | |
| SCHEMBL8113839 | 0.86 | FAAH (0.60) | PTGIRKDM4EFAAHHDAC1 | |
| SCHEMBL8103917 | 0.81 | PTGIR (0.43) | PTGIRCYP1A2 | |
| SCHEMBL9200683 | 0.80 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL9198869 | 0.80 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL9202086 | 0.80 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL9206363 | 0.80 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL9206357 | 0.80 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL19926859 | 0.79 | PTGS2 (0.54) | HSD17B10 | |
| Water SCHEMBL9203487 | 0.78 | PTGIR (0.97) | PTGIRKDM4ETSHRHSD17B10GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626969-B1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5663053-A | COENZYME A TRANSACYLASE FOR SCREENING | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5648373-A | CoA-IT and PAF inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0626969-A4 | CoA-IT AND PAF INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0626969-A1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993016674-A1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-02 | — | — | WO | disclosed |
| EP-0548227-A1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004334-A1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |