Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843728 | 1.00 | FAAH (0.61) | FAAHMEN1KMT2ABCHECNR1 | |
| SCHEMBL8843828 | 1.00 | FAAH (0.61) | FAAHMEN1KMT2ABCHECNR1 | |
| SCHEMBL8843705 | 0.93 | FAAH (0.54) | FAAHMEN1KMT2ABCHE | |
| SCHEMBL8112194 | 0.93 | FAAH (0.54) | FAAHMEN1KMT2ABCHE | |
| SCHEMBL8104102 | 0.86 | FAAH (0.80) | FAAHMEN1KMT2A | |
| SCHEMBL8103910 | 0.86 | FAAH (0.80) | FAAHMEN1KMT2A | |
| SCHEMBL8112613 | 0.86 | FAAH (0.80) | FAAHMEN1KMT2A | |
| SCHEMBL8843453 | 0.81 | FAAH (0.47) | FAAHMEN1KMT2A | |
| SCHEMBL8844406 | 0.81 | FAAH (0.47) | FAAHMEN1KMT2A | |
| SCHEMBL8103885 | 0.81 | FAAH (0.61) | FAAHBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626969-B1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5663053-A | COENZYME A TRANSACYLASE FOR SCREENING | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5648373-A | CoA-IT and PAF inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-15 | — | — | US | disclosed |