Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112194 | 1.00 | FAAH (0.54) | FAAHBCHEMEN1KMT2AKDM4E | |
| SCHEMBL8843828 | 0.93 | FAAH (0.61) | FAAHBCHEMEN1KMT2A | |
| SCHEMBL8103913 | 0.93 | FAAH (0.61) | FAAHBCHEMEN1KMT2A | |
| SCHEMBL8843728 | 0.93 | FAAH (0.61) | FAAHBCHEMEN1KMT2A | |
| SCHEMBL8104170 | 0.88 | FAAH (0.70) | FAAHBCHEMEN1KMT2AGAA | |
| SCHEMBL8104149 | 0.88 | FAAH (0.70) | FAAHBCHEMEN1KMT2AGAA | |
| SCHEMBL8112175 | 0.86 | FAAH (0.55) | FAAHBCHE | |
| SCHEMBL8112509 | 0.86 | FAAH (0.55) | FAAHBCHE | |
| SCHEMBL27241995 | 0.83 | BCHE (0.58) | FAAHBCHEKDM4ENPSR1ALDH1A1 | |
| SCHEMBL27207545 | 0.83 | BCHE (0.58) | FAAHBCHEKDM4ENPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663053-A | COENZYME A TRANSACYLASE FOR SCREENING | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5648373-A | CoA-IT and PAF inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-15 | — | — | US | disclosed |