SCHEMBL8103930

SCHEMBL8103930

CSc1cccc(C2NC(=O)CS2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.43
GAA P10253 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
DRD2 P14416 1/20 0.36
DRD1 P21728 1/20 0.36
DRD4 P21917 1/20 0.36
DRD5 P21918 1/20 0.36
DRD3 P35462 1/20 0.36
ALOX5 P09917 1/20 0.35
BACE1 P56817 2/20 0.35
HPGD P15428 3/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089821 0.80 GFER (0.56) GFERL3MBTL1GAASMN1; SMN2MEN1
SCHEMBL8103950 0.78 GFER (0.45) GFERL3MBTL1GAASMN1; SMN2
SCHEMBL8096935 0.77 GFER (0.52) GFERL3MBTL1GAASMN1; SMN2HPGD
SCHEMBL8089828 0.77 SMN1; SMN2 (0.54) GFERL3MBTL1GAASMN1; SMN2HPGD
SCHEMBL8099174 0.77 GFER (0.52) GFERL3MBTL1GAASMN1; SMN2ALDH1A1
SCHEMBL8089772 0.77 GFER (0.52) GFERL3MBTL1GAASMN1; SMN2HPGD
SCHEMBL8090311 0.77 GFER (0.63) GFERL3MBTL1GAASMN1; SMN2MEN1
SCHEMBL5450446 0.76 SMN1; SMN2 (0.59) GFERL3MBTL1GAASMN1; SMN2HPGD
SCHEMBL27294890 0.75 GFER (0.51) GFERL3MBTL1GAASMN1; SMN2DRD2
SCHEMBL8103620 0.73 GFER (0.49) GFERL3MBTL1GAASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed