SCHEMBL8103950

SCHEMBL8103950

CSc1cc(O)cc(C2NC(=O)CS2)c1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293946 0.76 GFER (0.44) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL27420663 0.75 GFER (0.43) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL9388818 0.74 GFER (0.42) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL27293941 0.74 CA12 (0.49) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL27293942 0.73 GFER (0.41) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL27316701 0.71 GFER (0.42) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL28866260 0.68 GFER (0.50) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL28255437 0.67 GFER (0.49) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL5450446 0.64 SMN1; SMN2 (0.59) GFERL3MBTL1SMN1; SMN2GAA
SCHEMBL70250 0.63 BACE1 (0.50) SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed