SCHEMBL8103983

SCHEMBL8103983

O=C1CCON1c1ccccc1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 12/20 0.44
TDP1 Q9NUW8 8/20 0.44
AKR1C3 P42330 1/20 0.43
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
NOTUM Q6P988 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11036457 0.76 KEAP1 (0.40) L3MBTL1KDM4EMAPTNOTUM
SCHEMBL8098473 0.76 L3MBTL1 (0.46) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL8098852 0.75 L3MBTL1 (0.45) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL8099198 0.75 L3MBTL1 (0.45) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL8098441 0.75 L3MBTL1 (0.45) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL19962678 0.75 MEN1 (0.45) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL15055196 0.74 L3MBTL1 (0.44) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL30483507 0.71 MEN1 (0.41) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL8098688 0.71 L3MBTL1 (0.44) L3MBTL1TDP1AKR1C3KDM4EMAPT
SCHEMBL8105921 0.71 L3MBTL1 (0.44) L3MBTL1TDP1AKR1C3KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed