Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090296 | 0.86 | ALDH1A1 (0.52) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7096455 | 0.85 | ALDH1A1 (0.53) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7453399 | 0.82 | ALDH1A1 (0.48) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7090289 | 0.79 | ALDH1A1 (0.53) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7093657 | 0.79 | ALDH1A1 (0.58) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7096453 | 0.78 | ALDH1A1 (0.51) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL6389795 | 0.78 | ALDH1A1 (0.56) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7091005 | 0.78 | ALDH1A1 (0.56) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7092696 | 0.77 | ALDH1A1 (0.52) | ALDH1A1DRD3CYP2D6CYP2C9ALOX15 | |
| SCHEMBL28357196 | 0.72 | SGMS2 (0.76) | NPSR1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084130-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |