Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.58 |
| ▸ | NPC1 | O15118 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067851 | 0.82 | TSHR (0.65) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL356367 | 0.81 | PTK2 (0.62) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL29883001 | 0.81 | PTK2 (0.62) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL2659431 | 0.81 | ALDH1A1 (0.58) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL29557123 | 0.81 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| Ammonia Solution, Strong SCHEMBL27883856 | 0.79 | PTK2 (0.61) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL1504119 | 0.79 | TSHR (0.61) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL28015608 | 0.79 | NPC1 (0.49) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL9413742 | 0.78 | ALDH1A1 (0.53) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Lithium SCHEMBL208951 | 0.78 | TSHR (0.59) | RAB9ANPC1MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1292781-A | Antiviral medicine | MEDIVIR AB (SE) | 2001-04-25 | — | — | CN | claimed |
| WO-2016112236-A1 | CYCLIC UREAS AS INHIBITORS OF ROCK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-07-14 | — | — | WO | disclosed |
| EP-1054867-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999036406-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 1999-07-22 | — | — | WO | disclosed |
| EP-0706514-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995006034-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1995-03-02 | — | — | WO | disclosed |