Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8095878 | 0.99 | EPHX2 (0.40) | EPHX2SLC9A1DDR1SLC9A2KLKB1 | |
| SCHEMBL17336046 | 0.85 | PLAU (0.37) | SLC9A1SLC9A2KLKB1PLAU | |
| SCHEMBL8743798 | 0.83 | PLK1 (0.39) | SLC9A1PLAU | |
| Hydrochloric Acid SCHEMBL8813212 | 0.83 | PLAU (0.38) | SLC9A1SLC9A2KLKB1PLAU | |
| Hydrochloric Acid SCHEMBL8743781 | 0.82 | PLK1 (0.38) | PLAU | |
| Hydrochloric Acid SCHEMBL8896876 | 0.81 | SCN2A (0.40) | PLAU | |
| SCHEMBL8743820 | 0.80 | SLC9A1 (0.40) | SLC9A1SLC9A2PLAU | |
| SCHEMBL8104315 | 0.80 | SLC9A1 (0.56) | SLC9A1SLC9A2 | |
| SCHEMBL8334682 | 0.79 | VCAM1 (0.47) | EPHX2 | |
| Hydrochloric Acid SCHEMBL7608239 | 0.79 | DDR1 (0.38) | SLC9A1DDR1SLC9A2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702001-B1 | Trifluoro-propyl-substituted benzoylguanidinens and their use as medicament or diagnostic agent | HOECHST AG (DE) | 2000-08-23 | — | — | EP | claimed |
| US-5869531-A | NO UNDESIREABLE SALIDIURETIC PROPERTIES; TREATING ISCHEMIA INDUCED DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |