Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP5 | P45974 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104425 | 1.00 | TBXAS1 (0.53) | TBXAS1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5105348 | 0.90 | TBXAS1 (0.61) | TBXAS1RAB9ANPC1ALDH1A1PDE4B | |
| SCHEMBL8110210 | 0.87 | MEN1 (0.48) | TBXAS1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8110219 | 0.87 | MEN1 (0.48) | TBXAS1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8110119 | 0.79 | USP5 (0.51) | TBXAS1RAB9ANPC1SMN1; SMN2USP5 | |
| SCHEMBL8106685 | 0.77 | TBXAS1 (0.85) | TBXAS1 | |
| SCHEMBL8106687 | 0.77 | TBXAS1 (0.85) | TBXAS1 | |
| SCHEMBL9639091 | 0.76 | CA1 (0.57) | TBXAS1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4743751 | 0.73 | MEN1 (0.68) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10070206 | 0.71 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103743-A | Unsaturated amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (US) | 2000-08-15 | — | — | US | disclosed |