SCHEMBL810449

SCHEMBL810449

C=Cc1ccc(C)cc1CCC(C)Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
HTR1D P28221 1/20 0.31
HTR1B P28222 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR1E P28566 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR7 P34969 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810459 0.84 TAAR1 (0.33) SRCTAAR1TP53TDP1CYP1A2
SCHEMBL809863 0.84 HTR2A (0.31) MAPTHTR1AADRA2ADRD2ADRA2B
SCHEMBL809944 0.80 HTR2A (0.38) TAAR1ALDH1A1HTR1AADRA2AADRA2B
SCHEMBL809639 0.78 L3MBTL1 (0.32) TAAR1ALDH1A1MAPK1L3MBTL1
SCHEMBL809443 0.78 SLC6A2 (0.40) ALDH1A1SLC6A4SLC6A3
SCHEMBL3629044 0.78 TAAR1 (0.37) SRCTAAR1ALDH1A1MAPTTHRB
SCHEMBL809697 0.77 MAPT (0.39) SRCTAAR1ALDH1A1MAPTTHRB
SCHEMBL11027744 0.76 ALDH1A1 (0.35) SRCTAAR1ALDH1A1MAPTTHRB
SCHEMBL810252 0.75 NPSR1 (0.43) SRCTAAR1ALDH1A1MAPTTHRB
SCHEMBL10751686 0.75 TP53 (0.36) SRCTAAR1ALDH1A1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012015977-A3 HIGHLY PORTABLE AND STABLE WORK STATION HERSCHLER MATTHEW B (US) 2012-05-10 WO disclosed
EP-2192645-B1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2011-11-30 EP disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed