Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784253 | 0.82 | TSHR (0.39) | TSHRL3MBTL1LMNAALDH1A1HSD17B10 | |
| SCHEMBL10900049 | 0.81 | L3MBTL1 (0.50) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL7784255 | 0.80 | L3MBTL1 (0.40) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL7778506 | 0.79 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1HSD17B10 | |
| SCHEMBL11616026 | 0.76 | L3MBTL1 (0.54) | L3MBTL1LMNAPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL7784246 | 0.76 | L3MBTL1 (0.40) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL11587569 | 0.76 | BIRC2 (0.49) | TSHRL3MBTL1LMNAHSD17B10BIRC2 | |
| SCHEMBL6138555 | 0.76 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1FOLH1 | |
| SCHEMBL2855754 | 0.75 | — | — | |
| SCHEMBL20767532 | 0.74 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |