⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18966483 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL8429080 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL11525673 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL2597017 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL5829754 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL4113305 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL8987158 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL4283433 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL8726527 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL305297 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945557-B | Fatty acid derivatives labeled with positron radionuclides | 安斯泰来制药株式会社 | 2024-06-04 | — | — | CN | disclosed |
| US-20230065079-A1 | FATTY ACID DERIVATIVE LABELED WITH POSITRON-EMITTING RADIONUCLIDE | ASTELLAS PHARMA INC. (JP) | 2023-03-02 | — | — | US | disclosed |
| EP-4095126-A1 | FATTY ACID DERIVATIVE LABELED BY POSITRON-EMITTING NUCLIDE | Astellas Pharma Inc. (JP) | 2022-11-30 | — | — | EP | disclosed |
| CN-114945557-A | Fatty acid derivatives labelled with positron-emitting radionuclides | 安斯泰来制药株式会社 | 2022-08-26 | — | — | CN | disclosed |
| WO-2021145403-A1 | FATTY ACID DERIVATIVE LABELED BY POSITRON-EMITTING NUCLIDE | アステラス製薬株式会社 | 2021-07-22 | — | — | WO | disclosed |
| US-10647747-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2018-04-19 | — | — | US | disclosed |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2018-04-19 | — | — | US | disclosed |
| CN-104789579-B | Thioesterase and application thereof | 奇华顿股份有限公司 | 2018-04-03 | — | — | CN | disclosed |
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |
| EP-0051284-B1 | NOVEL THIAPROSTAGLANDIN E1 DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1985-01-09 | — | — | EP | disclosed |
| US-4466980-A | Thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-08-21 | — | — | US | disclosed |
| EP-0051284-A1 | Novel thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceuticals containing these compounds | TEIJIN LIMITED (JP) | 1982-05-12 | — | — | EP | disclosed |
| US-4320070-A | ION EXCHANGE RESIN CATALYST | PPG INDUSTRIES, INC. (US) | 1982-03-16 | — | — | US | disclosed |
| US-4273725-A | Process for preparing chlorothiolformates | PPG INDUSTRIES, INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4268456-A | FROM A MERCAPTAN AND PHOSGENE, QUATERNARY AMMONIUM SALT CATALYST | PPG INDUSTRIES, INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4229588-A | FROM A MERCAPTOALKYL ESTER CONTACTED WITH A HALOGEN | PHILLIPS PETROLEUM COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4175201-A | Chemical synthesis | UNIVERSITY OF CHICAGO (US) | 1979-11-20 | — | — | US | disclosed |
| US-4110444-A | MODIFY THE STRENGTH OF BIOLOGICAL MEMBRANES | THE CALIFORNIA POLYTECHNIC STATE UNIVERSITY FOUNDATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4018820-A | Chemical synthesis | THE UNIVERSITY OF CHICAGO (US) | 1977-04-19 | — | — | US | disclosed |