Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104395 | 0.89 | MAOB (0.35) | POLBMAPTTDP1NPSR1 | |
| SCHEMBL8104610 | 0.85 | POLB (0.35) | POLBGAAMEN1KMT2A | |
| SCHEMBL8113483 | 0.80 | NPC1 (0.35) | KMT2AMAPTTDP1XBP1NPSR1 | |
| SCHEMBL8113746 | 0.74 | MAOB (0.39) | — | |
| SCHEMBL8120742 | 0.73 | MAOB (0.36) | — | |
| SCHEMBL8114599 | 0.73 | FASN (0.36) | MAPTNPSR1 | |
| SCHEMBL8104624 | 0.70 | RORC (0.36) | MEN1KMT2ANPSR1 | |
| SCHEMBL8104607 | 0.69 | RORC (0.36) | MEN1KMT2ANPSR1 | |
| SCHEMBL8114528 | 0.68 | FFAR1 (0.38) | MEN1KMT2A | |
| SCHEMBL8113743 | 0.65 | FNTA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |