Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120737 | 0.88 | MAOB (0.35) | ABCB1FFAR1FFAR4SLC16A3SLC16A1 | |
| SCHEMBL8113743 | 0.86 | FNTA (0.39) | FFAR1FFAR4MAOBFNTAFNTB | |
| SCHEMBL8104624 | 0.85 | RORC (0.36) | RORCABCB1MEN1KMT2AALDH1A1 | |
| SCHEMBL8104036 | 0.78 | MCHR1 (0.38) | RORCALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8104401 | 0.77 | MCHR1 (0.38) | RORCKMT2AALDH1A1LMNAHTT | |
| SCHEMBL8114528 | 0.77 | FFAR1 (0.38) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8104391 | 0.72 | MAOB (0.34) | ABCB1FFAR1FFAR4MAOBFNTA | |
| SCHEMBL8104710 | 0.71 | FNTA (0.40) | FFAR1FFAR4MAOBFNTAFNTB | |
| SCHEMBL8114479 | 0.70 | TSPO (0.48) | KMT2AFFAR1FFAR4MAOB | |
| SCHEMBL30194819 | 0.69 | FFAR1 (0.48) | FFAR1FFAR4MAOBALKBH1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |