Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 7/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097840 | 1.00 | CNR2 (0.48) | CNR2CNR1SMPD1MTNR1AMTNR1B | |
| SCHEMBL8097843 | 1.00 | CNR2 (0.48) | CNR2CNR1SMPD1MTNR1AMTNR1B | |
| SCHEMBL8104774 | 1.00 | CNR2 (0.48) | CNR2CNR1SMPD1MTNR1AMTNR1B | |
| SCHEMBL8097222 | 0.92 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL8104747 | 0.90 | MTNR1A (0.59) | CNR2CNR1MTNR1AMTNR1B | |
| SCHEMBL8088386 | 0.90 | MTNR1A (0.59) | CNR2CNR1MTNR1AMTNR1B | |
| SCHEMBL8097808 | 0.90 | MTNR1A (0.59) | CNR2CNR1MTNR1AMTNR1B | |
| SCHEMBL8097806 | 0.90 | MTNR1A (0.59) | CNR2CNR1MTNR1AMTNR1B | |
| SCHEMBL8104745 | 0.90 | MTNR1A (0.59) | CNR2CNR1MTNR1AMTNR1B | |
| SCHEMBL8088384 | 0.90 | MTNR1A (0.59) | CNR2CNR1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | claimed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |