Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MYOC | Q99972 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940372 | 0.92 | MAPT (0.53) | DDX3XMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7622067 | 0.90 | MAPT (0.57) | DDX3XMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7623586 | 0.87 | MAPT (0.64) | MEN1KMT2AMAPTNPSR1MAPK1 | |
| SCHEMBL7626118 | 0.86 | MAPT (0.55) | DDX3XMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7622098 | 0.85 | MAPT (0.61) | MEN1KMT2AMAPTNPSR1MAPK1 | |
| SCHEMBL6941701 | 0.85 | ATM (0.63) | MEN1KMT2AMAPTNPSR1MAPK1 | |
| SCHEMBL8104822 | 0.83 | MAPT (0.65) | MEN1KMT2AMAPTNPSR1MAPK1 | |
| SCHEMBL6937552 | 0.82 | ATM (0.54) | MEN1KMT2AMAPTNPSR1MAPK1 | |
| SCHEMBL8109117 | 0.82 | MEN1 (0.64) | MEN1KMT2AMAPTNPSR1MAPK1 | |
| SCHEMBL6943829 | 0.82 | RORC (0.52) | MEN1KMT2AMAPTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042278-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | Slovakofarma, A.S. (SK) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032437-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA, A.S. (SK) | 1999-07-01 | — | — | WO | disclosed |