Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MYOC | Q99972 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103149 | 0.88 | MEN1 (0.67) | RORCMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6943827 | 0.85 | ABCG2 (0.68) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6941701 | 0.84 | ATM (0.63) | RORCMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6941542 | 0.83 | TRPV1 (0.63) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL8104822 | 0.82 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7622098 | 0.82 | MAPT (0.61) | RORCMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8104860 | 0.82 | DDX3X (0.57) | RORCMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6937552 | 0.81 | ATM (0.54) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6940403 | 0.81 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17978450 | 0.81 | HTT (0.60) | RORCMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042278-B1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA AS (SK) | 2003-03-05 | — | — | EP | disclosed |
| US-6444691-B1 | ANTICHOLESTEROL AGENTS | SOLVAKOFARMA, A.S. (SK) | 2002-09-03 | — | — | US | disclosed |
| EP-1042278-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | Slovakofarma, A.S. (SK) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032437-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA, A.S. (SK) | 1999-07-01 | — | — | WO | disclosed |