Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632959 | 0.87 | HSPB1 (0.66) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11721323 | 0.84 | HSPB1 (0.54) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19950759 | 0.83 | ALDH1A1 (0.65) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9087468 | 0.82 | HSPB1 (0.59) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28129762 | 0.81 | MEN1 (0.55) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10337156 | 0.81 | HTT (0.60) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2285909 | 0.81 | GAA (0.69) | ALDH1A1MAPTMEN1KMT2AGAA | |
| 2,4'-Oxybis(Nitrobenzene) SCHEMBL9474586 | 0.81 | HSPB1 (0.62) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27739212 | 0.80 | MEN1 (0.57) | HSPB1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5082634 | 0.79 | ALDH1A1 (0.66) | HSPB1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042278-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | Slovakofarma, A.S. (SK) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032437-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA, A.S. (SK) | 1999-07-01 | — | — | WO | disclosed |
| US-4880838-A | INSECTICIDES | RHONE-POULENC (NL) | 1989-11-14 | — | — | US | disclosed |
| EP-0215841-B1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION | RHONE-POULENC NEDERLAND B.V. (NL) | 1988-11-17 | — | — | EP | disclosed |
| EP-0220840-A2 | Pesticidal 1-(4-aryloxyphenyl)-3-benzoyl urea compounds, processes for their preparation, and pesticidal compositions and methods of controlling pests employing said compounds | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-05-06 | — | — | EP | disclosed |
| EP-0215841-A1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION. | UNION CARBIDE CORP (US) | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005780-A1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1986-10-09 | — | — | WO | disclosed |