Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661013 | 0.76 | SLC6A2 (0.44) | SLC6A2SIGMAR1SLC6A3SLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4021178 | 0.75 | SLC6A2 (0.43) | SLC6A2SIGMAR1SLC6A3SLC6A4CYP2D6 | |
| SCHEMBL8112597 | 0.75 | SLC6A2 (0.43) | SLC6A2SIGMAR1SLC6A3SLC6A4CYP2D6 | |
| SCHEMBL27499030 | 0.66 | SLC22A1 (0.47) | SLC6A2SLC6A4 | |
| SCHEMBL8105073 | 0.65 | PRCP (0.53) | SIGMAR1SLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8320850 | 0.64 | ALDH1A1 (0.51) | SIGMAR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8107104 | 0.64 | ALDH1A1 (0.54) | SIGMAR1SLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8097372 | 0.64 | CHRM2 (0.45) | SLC6A2SIGMAR1SLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8106991 | 0.64 | SLC6A2 (0.50) | SLC6A2SIGMAR1SLC6A3SLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8107066 | 0.64 | CHRM2 (0.45) | SLC6A2SIGMAR1SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |