Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661013 | 0.86 | SLC6A2 (0.44) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL4021178 | 0.85 | SLC6A2 (0.43) | SLC6A4SLC6A2 | |
| SCHEMBL8112597 | 0.83 | SLC6A2 (0.43) | OPRM1SLC6A4SLC6A2 | |
| SCHEMBL8320731 | 0.80 | SLC22A1 (0.51) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8316995 | 0.79 | SLC22A1 (0.50) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL8320764 | 0.76 | SLC22A1 (0.50) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL29204727 | 0.76 | SLC22A1 (0.54) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL6662356 | 0.75 | SLC6A2 (0.43) | SLC22A1SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8319705 | 0.74 | SLC22A1 (0.52) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8318722 | 0.73 | OPRM1 (0.48) | SLC22A1OPRM1OPRD1OPRK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226886-A | Arylcycloalkane carboxylic acid esters, their use, pharmaceutical compositions and process for their preparation | PHARMACIA & UPJOHN AB (SE) | 1999-08-25 | — | — | CN | claimed |
| CN-1226886-A | Arylcycloalkane carboxylic acid esters, their use, pharmaceutical compositions and process for their preparation | PHARMACIA & UPJOHN AB (SE) | 1999-08-25 | — | — | CN | disclosed |