Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.68 |
| ▸ | CTSS | P25774 | 4/20 | 0.68 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KYNU | Q16719 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15889688 | 1.00 | CTSL (0.68) | CTSLCTSSTRPM8CTSKCTSB | |
| SCHEMBL9782142 | 1.00 | CTSL (0.68) | CTSLCTSSTRPM8CTSKCTSB | |
| SCHEMBL15878934 | 1.00 | CTSL (0.68) | CTSLCTSSTRPM8CTSKCTSB | |
| SCHEMBL15317910 | 1.00 | CTSL (0.68) | CTSLCTSSTRPM8CTSKCTSB | |
| SCHEMBL20538251 | 0.93 | CTSL (0.70) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL2678260 | 0.93 | CTSL (0.70) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL2678259 | 0.93 | CTSL (0.70) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL1491407 | 0.90 | CTSL (0.70) | CTSLCTSSTRPM8CTSKCTSB | |
| SCHEMBL10663359 | 0.90 | CTSL (0.70) | CTSLCTSSTRPM8CTSKCTSB | |
| SCHEMBL14561285 | 0.90 | CTSL (0.70) | CTSLCTSSTRPM8CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |