Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethion SCHEMBL1071058 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL8200128 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| Ethion SCHEMBL9343797 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| Ethion SCHEMBL26750 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL3817924 | 0.82 | TSHR (0.48) | ALDH1A1HSD17B10CYP3A4TSHRTDP1 | |
| Ethion SCHEMBL29173186 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| Ethion SCHEMBL8388102 | 0.80 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| Ethion SCHEMBL6047155 | 0.79 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL11439808 | 0.79 | ACHE (0.38) | ALDH1A1HSD17B10CYP3A4TSHRTDP1 | |
| SCHEMBL5933951 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034128-A | PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-07 | — | — | US | disclosed |
| EP-0785923-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-4138548-A | Acaricidal pyridinium salts | FISONS LIMITED (GB) | 1979-02-06 | — | — | US | disclosed |
| US-4125617-A | Acaricidal pyridinium salts | FISONS LIMITED (GB) | 1978-11-14 | — | — | US | disclosed |
| US-4013669-A | ESTER-PYRIDINIUM COMPOUNDS AS ACARICIDES | FISONS LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |