SCHEMBL8105599

SCHEMBL8105599

CCC(C)(C)c1ccc(OCC(=O)Nc2cccc(N[C]=O)c2)c(C(C)(C)CC)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
NPSR1 Q6W5P4 5/20 0.54
MAPK1 P28482 5/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 5/20 0.43
HTT P42858 4/20 0.43
UBE2N P61088 2/20 0.43
HIF1A Q16665 1/20 0.43
EPAS1 Q99814 1/20 0.43
GLA P06280 1/20 0.43
MITF O75030 1/20 0.43
LMNA P02545 1/20 0.42
STAT3 P40763 1/20 0.42
RAD52 P43351 1/20 0.42
RCE1 Q9Y256 1/20 0.42
MDH1 P40925 1/20 0.42
MDH2 P40926 1/20 0.42
RAB9A P51151 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536704 0.88 SMN1; SMN2 (0.54) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL10525796 0.88 SMN1; SMN2 (0.56) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL9340133 0.86 SMN1; SMN2 (0.61) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL11465451 0.86 MEN1 (0.54) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL11703999 0.85 ALDH1A1 (0.56) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL7063221 0.84 SMN1; SMN2 (0.55) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL9472399 0.84 KMT2A (0.55) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL7063227 0.84 SMN1; SMN2 (0.54) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL7747075 0.84 MEN1 (0.54) MEN1KMT2ASMN1; SMN2NPSR1MAPK1
SCHEMBL11793477 0.82 SMN1; SMN2 (0.52) MEN1KMT2ASMN1; SMN2NPSR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156489-A Silver halide photosensitive material KONICA CORPORATION (JP) 2000-12-05 US disclosed
US-4241168-A TWO-EQUIVALENT MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-12-23 US disclosed
US-4040836-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4040835-A Two-equivalent magenta couplers with amido coupling-off groups FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4029508-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-06-14 US disclosed