Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096606 | 0.86 | SLC6A4 (0.50) | HTR2ASLC6A4HTR1A | |
| SCHEMBL8149530 | 0.84 | SLC6A4 (0.51) | SLC6A4HTR1AHTR6 | |
| SCHEMBL8103912 | 0.84 | CYP1A2 (0.54) | MTNR1AMTNR1BHTR2ASLC6A4HTR1A | |
| SCHEMBL8109654 | 0.84 | SLC6A4 (0.68) | HTR2AHTR2CHTR2BSLC6A4HTR1A | |
| SCHEMBL8103893 | 0.81 | SLC6A4 (0.72) | HTR2ASLC6A4HTR1AHTR6 | |
| SCHEMBL8103889 | 0.78 | SLC6A4 (0.51) | SLC6A4HTR1A | |
| SCHEMBL4671021 | 0.77 | HTR2A (0.59) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL18474137 | 0.77 | MTNR1A (0.65) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL4671600 | 0.74 | SLC6A4 (0.49) | MTNR1AMTNR1BHTR2ASLC6A4HTR1A | |
| SCHEMBL7710792 | 0.74 | HTR1D (0.67) | MTNR1AMTNR1BHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |