Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149530 | 0.91 | SLC6A4 (0.51) | SLC6A4IDO1OPRM1OPRK1OPRL1 | |
| SCHEMBL8109654 | 0.80 | SLC6A4 (0.68) | SLC6A4ADRA1DOPRM1OPRK1OPRL1 | |
| SCHEMBL8096606 | 0.80 | SLC6A4 (0.50) | SLC6A4IDO1HTR1A | |
| SCHEMBL8103912 | 0.80 | CYP1A2 (0.54) | SLC6A4ADRA1DOPRM1OPRK1OPRL1 | |
| SCHEMBL8103890 | 0.78 | SLC6A4 (0.53) | SLC6A4ADRA1DIDO1OPRM1OPRK1 | |
| SCHEMBL8105710 | 0.78 | MTNR1A (0.53) | SLC6A4HTR1A | |
| SCHEMBL8103893 | 0.78 | SLC6A4 (0.72) | SLC6A4HTR1A | |
| SCHEMBL4675206 | 0.75 | SLC6A4 (0.58) | SLC6A4IDO1OPRM1OPRK1OPRL1 | |
| SCHEMBL4672939 | 0.73 | OPRM1 (0.50) | SLC6A4ADRA1DOPRM1OPRK1OPRL1 | |
| SCHEMBL8106283 | 0.73 | ALDH1A1 (0.47) | SLC6A4IDO1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |