Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897061 | 0.77 | PLD1 (0.40) | PLD1GRM1KDM4EGRIN2BGRIN2D | |
| SCHEMBL2176945 | 0.74 | L3MBTL3 (0.45) | KDM4EGRIN2BALDH1A1HSD17B10DRD2 | |
| SCHEMBL60079 | 0.74 | PLD1 (0.66) | PLD1KDM4EGRIN2BGRIN2DGRIN3B | |
| SCHEMBL3154137 | 0.74 | PLD1 (0.66) | PLD1KDM4EGRIN2BGRIN2DGRIN3B | |
| SCHEMBL29389926 | 0.74 | PLD1 (0.66) | PLD1KDM4EGRIN2BGRIN2DGRIN3B | |
| SCHEMBL19540186 | 0.74 | PLD1 (0.66) | PLD1KDM4EGRIN2BGRIN2DGRIN3B | |
| SCHEMBL28101766 | 0.73 | HRH3 (0.56) | PLD1 | |
| Hydrochloric Acid SCHEMBL10642748 | 0.72 | PLD1 (0.63) | PLD1KDM4EGRIN2BGRIN2DGRIN3B | |
| Lithium SCHEMBL31260780 | 0.72 | PLD1 (0.63) | PLD1KDM4EGRIN2BGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL30864277 | 0.72 | PLD1 (0.63) | PLD1KDM4EGRIN2BGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |