SCHEMBL8105745

SCHEMBL8105745

CC(F)C(O)c1ccccc1S(=O)(=O)NC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.41
PARG Q86W56 1/20 0.40
ALOX5AP P20292 9/20 0.38
FEN1 P39748 9/20 0.38
SLC6A4 P31645 1/20 0.38
HTR2A P28223 2/20 0.37
HTR2C P28335 2/20 0.37
KCNH2 Q12809 2/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 3/20 0.37
KMT2A Q03164 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
GMNN O75496 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14328457 0.80 NSD2 (0.47) NSD2PARGALOX5APFEN1LMNA
SCHEMBL9636843 0.80 SLC6A4 (0.42) NSD2PARGALOX5APFEN1SLC6A4
SCHEMBL27395960 0.79 CA12 (0.58) LMNAMAPTKMT2AKDM4EHPGD
SCHEMBL8111692 0.78 NSD2 (0.36) NSD2PARGALOX5APFEN1LMNA
SCHEMBL6574265 0.77 ALOX5AP (0.38) NSD2ALOX5APFEN1LMNAMAPT
SCHEMBL8615761 0.76 PARG (0.43) NSD2PARGALOX5APFEN1LMNA
SCHEMBL2803354 0.74 NSD2 (0.58) NSD2PARGALOX5APFEN1LMNA
SCHEMBL1790762 0.71 NSD2 (0.45) NSD2PARGALOX5APFEN1LMNA
SCHEMBL1790761 0.71 NSD2 (0.45) NSD2PARGALOX5APFEN1LMNA
SCHEMBL8615033 0.71 CA9 (0.44) NSD2PARGALOX5APFEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788486-B1 HERBICIDAL SULFONYL UREA DERIVATIVES KOREA RES INST CHEM TECH (KR) 2000-07-12 EP disclosed
US-5736628-A HERBICIDE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-04-07 US disclosed
WO-1996012708-A1 HERBICIDAL SULFONYL UREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-05-02 WO disclosed
US-5461025-A Herbicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-24 US disclosed
EP-0575378-A1 BENZENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-12-29 EP disclosed
WO-1992015568-A1 BENZENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-09-17 WO disclosed