SCHEMBL8615033

SCHEMBL8615033

CC(C)(C)NS(=O)(=O)c1ccccc1C(=O)CF

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 7/20 0.44
CA12 O43570 6/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
NSD2 O96028 2/20 0.42
PARG Q86W56 1/20 0.41
ALOX5AP P20292 3/20 0.39
FEN1 P39748 3/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
USP30 Q70CQ3 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9786904 0.80 CA1 (0.66) CA9CA12CA1CA2MMP1
SCHEMBL8615761 0.80 PARG (0.43) CA9CA12CA1CA2MMP1
SCHEMBL8804447 0.76 MEN1 (0.44) CA9CA12CA1CA2MMP1
SCHEMBL2803354 0.75 NSD2 (0.58) NSD2PARGALOX5APFEN1MAPT
SCHEMBL8642432 0.75 ALDH1A1 (0.36) MAPTNPSR1USP30
SCHEMBL8638381 0.73 LMNA (0.42) MAPT
SCHEMBL8105745 0.71 NSD2 (0.41) NSD2PARGALOX5APFEN1MAPT
SCHEMBL7247915 0.71 ALOX5AP (0.46) NSD2PARGALOX5APFEN1
SCHEMBL8615855 0.71 NSD2 (0.36) NSD2PARGALOX5APFEN1MAPT
SCHEMBL3583413 0.71 NSD2 (0.50) NSD2PARGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736628-A HERBICIDE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-04-07 US disclosed
US-5461025-A Herbicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-24 US disclosed
EP-0575378-A1 BENZENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-12-29 EP disclosed
WO-1992015568-A1 BENZENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-09-17 WO disclosed