SCHEMBL6574265

SCHEMBL6574265

CC(F)C(O)c1ncccc1S(=O)(=O)NC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 13/20 0.38
FEN1 P39748 13/20 0.38
NSD2 O96028 2/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
CA9 Q16790 1/20 0.36
USP30 Q70CQ3 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TRPV4 Q9HBA0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7806543 0.86 ALOX5AP (0.36) ALOX5APFEN1NSD2CA12CA1
SCHEMBL8106979 0.80 ALOX5AP (0.35) ALOX5APFEN1NSD2USP30TRPV4
SCHEMBL27713085 0.80 CA1 (0.44) ALOX5APFEN1CA12CA1CA2
SCHEMBL6572730 0.79 ALOX5AP (0.36) ALOX5APFEN1CA12CA1CA2
SCHEMBL6816857 0.78 PIK3C3 (0.33) ALOX5APCA12CA1CA2ADRB2
SCHEMBL6812765 0.78 ALDH1A1 (0.37) ALOX5APFEN1CA12CA1CA2
SCHEMBL8105745 0.77 NSD2 (0.41) ALOX5APFEN1NSD2USP30KDM4E
SCHEMBL6571896 0.76 ALOX5AP (0.33) ALOX5APFEN1USP30KDM4ESMN1; SMN2
SCHEMBL9217880 0.75 USP30 (0.35) ALOX5APFEN1NSD2CA12CA1
SCHEMBL9037582 0.73 ALOX5AP (0.49) ALOX5APFEN1NSD2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6806229-B1 SULFUR COMPOUNDS SUCH AS N-((4,6-DIMETHOXYPYRIMIDIN-2-YL) AMINOCARBONYL)-2-(2-FLUORO-1-METHOXYACTETOXY-N-PROPYL)PYRIDINE -3-SULFONAMIDE AND ISOMERS, USED AS PRE-AND/OR POST-EMERGENCE HERBICIDES LG LIFE SCIENCES (KR) 2004-10-19 US disclosed
US-6762305-B2 PRE- AND/OR POST-EMERGENCE TREATMENT IN RICE FARMING LG LIFE SCIENCES (KR) 2004-07-13 US disclosed
US-20040116298-A1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG LIFE SCIENCES 2004-06-17 US disclosed
EP-1334099-B1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD (KR) 2004-03-10 EP disclosed
EP-1334099-A4 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD (KR) 2003-08-13 EP disclosed
EP-1334099-A1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG Chem Investment Ltd. (KR) 2003-08-13 EP disclosed
WO-2002030921-A1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD. (KR) 2002-04-18 WO disclosed