Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771863 | 0.95 | TBXAS1 (0.65) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL8121773 | 0.92 | TBXAS1 (0.54) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7771744 | 0.91 | TBXAS1 (0.66) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7460400 | 0.88 | TBXAS1 (0.70) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL8112580 | 0.87 | TBXAS1 (0.56) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7459288 | 0.87 | TBXAS1 (0.69) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7776162 | 0.86 | TBXAS1 (0.72) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7467932 | 0.85 | TBXAS1 (0.73) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7220602 | 0.84 | TBXAS1 (0.68) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7463923 | 0.84 | TBXAS1 (0.72) | TBXAS1TBXA2RHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013667-A | Benzenesulfonylamine compounds, process for preparing them and pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0864561-A1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-16 | — | — | EP | disclosed |