Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115364 | 0.99 | ADRA1A (0.52) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29302 | 0.81 | MEN1 (0.57) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29372521 | 0.81 | MEN1 (0.57) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL10707097 | 0.81 | MEN1 (0.57) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL19668120 | 0.81 | MEN1 (0.57) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8607117 | 0.81 | MEN1 (0.57) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL31069910 | 0.81 | MEN1 (0.57) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3361977 | 0.79 | MEN1 (0.55) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL19631491 | 0.78 | MEN1 (0.49) | ADRA1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL30131126 | 0.78 | MEN1 (0.49) | ADRA1AKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |