Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548332 | 0.85 | CA12 (0.54) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL19897384 | 0.83 | CA12 (0.49) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL14423570 | 0.81 | TDP1 (0.51) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL29690328 | 0.81 | TDP1 (0.51) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL1011515 | 0.81 | MAOB (0.50) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL25056780 | 0.81 | CYP2A6 (0.45) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL15856512 | 0.81 | MAOA (0.50) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL15856460 | 0.81 | CYP2A6 (0.45) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL2996863 | 0.81 | CYP2A6 (0.65) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL8378402 | 0.80 | CYP2A6 (0.56) | MAOAMAOBCYP1A2CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601361-B1 | Water-soluble disazo compounds, process for their preparation and their use as dyestuffs | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 1998-11-04 | — | — | EP | claimed |
| US-6156815-A | Acid-curable binder systems containing 1,2-disulfones | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |
| US-5985950-A | Acid-curable binder systems containing 1,2 disulfones | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| US-4980508-A | Oxidation of 1,2-disulonyhydrazine compound with concentrated nitric acid | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-12-25 | — | — | US | disclosed |
| US-4980268-A | POLYAMIC ACID CONVERTIBLE TO POLYIMIDES | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |