Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628971 | 0.91 | — | — | |
| SCHEMBL20065224 | 0.81 | LMNA (0.50) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL6822537 | 0.79 | SMN1; SMN2 (0.45) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL7277181 | 0.77 | LMNA (0.45) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL22043008 | 0.77 | LMNA (0.45) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL11276999 | 0.76 | LMNA (0.46) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL2440165 | 0.76 | LMNA (0.41) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL8379227 | 0.76 | LMNA (0.54) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL5181091 | 0.76 | LMNA (0.54) | LMNAMITFSMN1; SMN2KDM4EGAA | |
| SCHEMBL131845 | 0.76 | LMNA (0.54) | LMNAMITFSMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404951-A1 | Polymerizable siloxane-quaternary amine copolymers | BAUSCH & LOMB INCORPORATED (US) | 2012-01-11 | — | — | EP | disclosed |