SCHEMBL2440165

SCHEMBL2440165

C=CC(=C)N1CCCCCC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
MITF O75030 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
STAT6 P42226 1/20 0.35
TP53 P04637 1/20 0.35
KDM4E B2RXH2 3/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2537024 0.92 LMNA (0.48) LMNAMITFSMN1; SMN2MAPTALDH1A1
SCHEMBL225114 0.81 LMNA (0.46) LMNAMITFSMN1; SMN2MAPTALDH1A1
SCHEMBL224075 0.81 LMNA (0.46) LMNAMITFSMN1; SMN2MAPTALDH1A1
Furan SCHEMBL28313557 0.80 LMNA (0.39) LMNASMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL4362204 0.78 LMNA (0.47) LMNAMITFSMN1; SMN2MAPTALDH1A1
SCHEMBL28220701 0.78 LMNA (0.50) LMNAMITFSMN1; SMN2MAPTALDH1A1
SCHEMBL6822537 0.76 SMN1; SMN2 (0.45) LMNAMITFSMN1; SMN2MAPTALDH1A1
SCHEMBL810605 0.76 LMNA (0.44) LMNAMITFSMN1; SMN2MAPTALDH1A1
SCHEMBL22043008 0.74 LMNA (0.45) LMNAMITFSMN1; SMN2MAPTALDH1A1
SCHEMBL7277181 0.74 LMNA (0.45) LMNAMITFSMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130198968-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS HERCULES LLC 2013-08-08 US claimed
EP-2545152-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS Isp Investments Inc. (US) 2013-01-16 EP claimed
WO-2011112944-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS ISP INVESTMENTS INC. (US) 2011-09-15 WO claimed
US-8993507-B2 Functional additives for cleansing compositions ISP INVESTMENTS INC. (US) 2015-03-31 US disclosed
US-20130198968-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS HERCULES LLC 2013-08-08 US disclosed
EP-2545152-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS Isp Investments Inc. (US) 2013-01-16 EP disclosed
WO-2011112944-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS ISP INVESTMENTS INC. (US) 2011-09-15 WO disclosed