Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118617 | 0.76 | TP53 (0.43) | OPRM1HDAC4TSHRCYP1A2PDE7A | |
| SCHEMBL8124069 | 0.76 | HTR2A (0.34) | MAPTMEN1KMT2ACYP1A2HSD11B1 | |
| SCHEMBL8105577 | 0.76 | KMT2A (0.44) | OPRM1MAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL8116256 | 0.70 | MEN1 (0.56) | OPRM1MAPTMEN1KMT2ATSHR | |
| SCHEMBL16868731 | 0.70 | S100A4 (0.43) | MAPTMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8609713 | 0.68 | HDAC4 (0.50) | OPRM1HDAC4TSHRACHEHSD11B1 | |
| SCHEMBL11096498 | 0.68 | MEN1 (0.40) | OPRM1HDAC4MEN1KMT2ASMN1; SMN2 | |
| Iodide SCHEMBL11093787 | 0.67 | MEN1 (0.39) | OPRM1HDAC4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11475250 | 0.67 | HDAC4 (0.35) | OPRM1HDAC4MAPTTSHRACHE | |
| SCHEMBL8117721 | 0.67 | MAOB (0.36) | OPRM1MAPTMEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |