Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326126 | 0.77 | SIGMAR1 (0.55) | KMT2ASIGMAR1CA12CA1CA2 | |
| SCHEMBL8106520 | 0.76 | OPRM1 (0.41) | KMT2AL3MBTL1ALDH1A1CYP3A4MAPT | |
| SCHEMBL8124069 | 0.72 | HTR2A (0.34) | KMT2AMAPTMGLL | |
| SCHEMBL8118617 | 0.72 | TP53 (0.43) | OPRM1OPRK1 | |
| SCHEMBL8105572 | 0.71 | IDO1 (0.42) | SIGMAR1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL11662275 | 0.69 | SIGMAR1 (0.47) | KMT2ASIGMAR1CA12CA1CA2 | |
| SCHEMBL613068 | 0.69 | SIGMAR1 (0.64) | KMT2ASIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL4229836 | 0.67 | SIRT1 (0.44) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL19291033 | 0.67 | SIGMAR1 (0.53) | KMT2ASIGMAR1CA12CA1CA2 | |
| Ethylene SCHEMBL8402234 | 0.67 | SIGMAR1 (0.60) | KMT2ASIGMAR1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |