Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553549 | 0.83 | SLC6A4 (0.48) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6553551 | 0.83 | SLC6A4 (0.48) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6577183 | 0.80 | OPRM1 (0.48) | SLC6A4DRD2SLC6A3 | |
| SCHEMBL6575266 | 0.80 | SLC6A4 (0.48) | SLC6A4DRD2SLC6A3SLC6A2 | |
| SCHEMBL6553215 | 0.79 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4576760 | 0.79 | SLC6A4 (0.45) | SLC6A4DRD2SLC6A3SLC6A2KDM4E | |
| SCHEMBL1721954 | 0.78 | SLC6A2 (0.55) | SLC6A4DRD2SLC6A3SLC6A2 | |
| SCHEMBL633352 | 0.78 | SLC6A2 (0.55) | SLC6A4DRD2SLC6A3SLC6A2 | |
| SCHEMBL633351 | 0.78 | SLC6A2 (0.55) | SLC6A4DRD2SLC6A3SLC6A2 | |
| SCHEMBL5830115 | 0.77 | SLC6A4 (0.39) | SLC6A4DRD2SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107307-A | PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0969005-A1 | Azabicyclic inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |